2025 Infiniti QX55 vs Lexus RX 350: a Complete Comparison

Shopping for a luxury SUV in Southern California? If you're weighing style, performance, and tech, the 2025 INFINITI QX55 and the 2025 Lexus RX 350 are likely at the top of your list. Both models offer sleek designs, strong performance, and advanced safety features—but which one is the better fit for your lifestyle? In this complete comparison, we break down how these two premium crossovers stack up in everything from fuel efficiency to cabin comfort.

Whether you’re commuting through Pomona, exploring the hills around Upland, or navigating the streets of Jurupa Valley, finding the right SUV matters. Read on to see how the INFINITI QX55 measures up to its Lexus rival—and if you’re ready to experience the QX55 firsthand, visit or contact INFINITI of Ontario for a personalized guest drive and expert insight.

2025 INFINITI QX55 vs Lexus RX 350: Which Luxury SUV is Right for You in Upland, Jurupa Valley, or Pomona?

Choosing the right luxury SUV can feel like a big task. If you live in Upland, Jurupa Valley, or Pomona, you need a vehicle that offers comfort, style, and smooth driving for your day-to-day trips. Two top picks this year are the 2025 INFINITI QX55 and the Lexus RX 350. Both bring a strong mix of tech, power, and design, but they serve different needs depending on what you value most.

The INFINITI QX55 2025 stands out for its bold coupe-like shape. It has a sleek roofline that gives it a sportier feel than many crossovers. The RX 350, on the other hand, leans toward a more classic SUV style. It's a little more upright and offers slightly more space in the back.

Here’s a quick look at how each model fits into your lifestyle in the Inland Empire:

QX55 Strengths:

• Sleek, sport-inspired shape
• Comes with all-wheel drive standard
• Advanced driver assist features in every trim
• Quiet, smooth ride on highways and in city traffic

RX 350 Strengths:

• Slightly more cargo space for large loads
• Smooth and refined engine
• More options for drivetrain (FWD or AWD)
• Well-known for long-term dependability

Living in a city like Pomona or Jurupa Valley means dealing with traffic, heat, and tight parking. The QX55 handles those needs well. It’s agile, quiet, and stylish. Drivers in Upland might also enjoy the extra grip and control that comes with its standard all-wheel drive—especially during trips through nearby hills or weekend drives out of town.

No matter which model you lean toward, it's smart to look at how the vehicle fits your daily life. Is a sleek design and extra tech more important than a bit of added cargo space? Do you want a unique style or prefer a more traditional SUV shape?

Each SUV has its perks. The QX55 gives a sporty edge and high-end look. The RX 350 brings a bit more room and brand name comfort. In the next sections, we’ll break down fuel use, comfort, tech, and more to help you choose the one that’s best for you.

Powertrain and Driving Performance on Southern California Roads

If you’re driving through Upland, Jurupa Valley, or Pomona, a strong, smooth ride matters. You want a luxury SUV that handles tight turns, quick stops, and highway speeds with ease. That’s where the INFINITI QX55 vs Lexus RX 350 comparison gets interesting.

The QX55 uses a 2.0-liter V4-turbo 4-cylinder engine. It makes 268 horsepower and comes standard with all-wheel drive. Power feels quick and easy, especially when merging onto freeways or climbing hills. The steering is tight, and the suspension keeps the ride sharp but not rough. This makes it a smart pick for drivers who want to feel in control at all times.

The Lexus RX 350 takes a different path. Its 2.4-liter turbo Inline-4 engine produces a bit more power—275 horsepower—but focuses more on comfort. The ride is soft and smooth. It glides over bumps and feels calm in busy traffic. You can get it in front-wheel drive or upgrade to all-wheel drive.

Here’s how the driving experience compares:

• The QX55 gives you a sporty, nimble feel. It's made for quick moves and tight handling.
• The RX 350 offers a more laid-back drive. It’s built for peace and ease over performance.
• If you prefer speed and control, the QX55 stands out.
• If you value quiet roads and comfort, the RX 350 may be a better fit.

Both models are strong options for Southern California drivers. Think about how you like to drive—fast and firm, or smooth and steady. That choice might lead you straight to your next SUV.

Fuel Efficiency and Commuting Comfort for Inland Empire Drivers

Long drives across the Inland Empire demand both smart fuel use and a calm ride. Whether you're heading from Pomona to Riverside or Upland to Ontario, the right SUV can save you gas and stress. That’s why comfort and fuel use matter just as much as power.

If you’re comparing fuel efficiency between the 2025 INFINITI QX55 and the Lexus RX 350, here’s what you should know: the QX55 gets 22 MPG in the city, 28 on the highway, and 25 combined. That’s right in line with the RX 350 FWD and slightly better than the AWD version of the RX. So if you’re looking for all-wheel drive capability without giving up efficiency, the QX55 holds its own—no need to sacrifice performance for MPG. Plus, every drop saved at the pump adds up, especially on longer commutes or weekend getaways.

Here’s a quick look at key points:

• Fuel Efficiency: Both models are close in MPG, with small gains going to the QX55.
• Ride Feel: The QX55 has a sport-tuned ride. The RX 350 feels more like a lounge on wheels.
• Cabin Noise: The RX 350 wins here with a near-silent cabin. The QX55 is quiet but still tuned for feedback.
• Seat Comfort: The QX55 gives more support for active drivers. The RX 350 uses softer seats.

This isn’t just about gas. It’s about how you feel at mile 50 of your drive home. That’s where real value shows up. For many Inland Empire drivers, that balance of comfort, style, and fuel use makes all the difference.

Cargo Space and Storage Versatility for Weekend Getaways

When it’s time to leave town for a quick trip, space and smart design start to matter more. You need room for bags, snacks, and gear—without giving up comfort. Both of these luxury SUVs are built to help with just that.

What That Actually Means for You

• INFINITI QX55 gives you more total space when you need it. If you’re folding down the rear seats to haul big items—like suitcases, camping gear, or a Costco haul—the QX55 delivers nearly 8 more cubic feet of usable cargo volume than the RX 350. That’s a significant edge.
• Lexus RX 350 edges ahead slightly with seats up, giving you about 2.7 more cubic feet of everyday cargo space behind the second row. It’s a small advantage for things like weekly groceries or a stroller—but you’ll feel the difference more when you fold the seats down, where it falls short.
• QX55 is built with versatility in mind. That rear cargo expansion means it’s better suited if you like to keep your options open—whether you're moving boxes or loading up for a road trip.

The Bottom Line

If your day-to-day mostly involves small hauls, either SUV will do the trick. But if you're the type who values flexibility—or just hates playing Tetris with your cargo—the INFINITI QX55 gives you the edge in total space. It’s a smart choice if you want that extra room without jumping up to a larger, less efficient SUV.

Want to check it out in person? INFINITI of Ontario would love to show you how it fits your life.

Interior Comfort and Cabin Quality That Reflects Your Lifestyle

Key Takeaways

• QX55 focuses on premium feel and comfort, especially with standard leather seating, a memory driver seat, and power lumbar support with more nuanced adjustability. If you share your car or have lower back issues, those features make a real difference day-to-day.
• Lexus RX 350 emphasizes tech and ambiance, with features like ambient interior lighting, multi-zone climate control, and a more customizable rear seat split (ideal if you often carry longer items like skis or boards).
• QX55 offers more ergonomic adjustability in both the front seats and rear seats, giving you and your passengers more control over comfort—plus, the auto-dimming rearview mirror is a small touch that adds noticeable nighttime driving comfort.
• Lexus uses NuLuxe®, a synthetic leather alternative, which is eco-conscious and durable, but if you’re craving the luxury of real leather, the QX55 delivers right out of the gate.

Final Thoughts

Both cabins are well-equipped and comfortable, but the 2025 INFINITI QX55 leans into luxury and driver personalization, making it a standout for anyone who values real leather, thoughtful seat adjustability, and comfort-enhancing details. It’s those small but impactful features that make every drive more enjoyable—especially when you're spending real time in your car.

Want to test those seats for yourself? Come in and feel the difference.

QX55 Technology Features vs Lexus RX Tech: What Stands Out

Expert Take: What You’ll Actually Notice

• INFINITI QX55 delivers a strong tech suite without needing extra subscriptions. You get voice commands, Wi-Fi, remote services, and wireless charging standard—features you’ll use every day.
• Lexus RX 350 has a bigger screen and more speakers, making it appealing if immersive sound and display size are priorities. However, some of its best features—like advanced voice control and navigation—require paid subscriptions and are 4G network-dependent.
• Both offer wireless Apple CarPlay® and Android Auto™, so no matter what smartphone you use, you’ll feel right at home.
• INFINITI’s approach is more streamlined and user-friendly out of the box. You don’t have to activate trials or pay to unlock everyday features like remote start, real-time updates, or connected services.

Bottom Line

If you're looking for tech that’s fully functional from day one without digging into your wallet, the INFINITI QX55 gives you more value and convenience. It’s built for drivers who want their car’s tech to just work—without the hassle of monthly add-ons.

Want to see how INFINITI tech feels in real time? We’d love to give you a hands-on demo.

Infiniti QX55 vs Lexus RX 350 Safety Features: What You Need to Know

When choosing a safe ride, it helps to look past just crash scores. A true safety suite works full-time to help you stay aware and in control—before, during, and even after a tough spot on the road.

In this Infiniti QX55 vs Lexus RX 350 comparison, both models bring strong peace of mind. Still, there are some key things to note that can help you decide which SUV best fits your needs.

How These Vehicles Bring You Peace of Mind

• INFINITI’s predictive systems give you a heads-up before trouble starts. For example, Predictive Forward Collision Warning watches not just the car in front of you—but the one in front of that, giving you time to react sooner.
• Blind Spot Intervention™ is more than just a warning. If you’re about to change lanes into another vehicle, QX55 can help steer you back into your lane. That’s a rare, proactive feature you won’t find in many competitors.
• Both models offer automatic emergency braking, adaptive cruise, and strong lane support, but only INFINITI gives you hands-on adaptive cruise with stop-and-go and Rear Automatic Braking, which comes in handy when backing into tight spots.
• Lexus comes with a solid suite of standard safety tech too, including 10 airbags and Road Sign Assist, but some features—like parking assist and cloud-connected safety functions—depend on subscriptions or trim levels.

Final Word

The 2025 INFINITI QX55 is loaded with smart, proactive safety tech that’s always looking out for you—from front to back and lane to lane. Its systems don’t just alert you—they intervene when needed, which is key if you’re driving with family or just want extra confidence in traffic.

If you're curious how these systems feel in real life, we’d love to show you in person. It’s safety you can see and feel.

Ready to Find Your Perfect Luxury SUV?

If you’re in Upland, Jurupa Valley, or Pomona, the Infiniti QX55 might be exactly what you’re looking for. But it’s not the only option we have to offer. At Infiniti of Ontario, we proudly carry a wide selection of luxury SUVs that can match any style or preference.

Take a closer look at our full lineup, including models like the 2025 Infiniti QX50 and QX60. These vehicles offer a variety of color, trim, and engine options designed to fit your needs. Whether you’re drawn to the sleek, sporty design of the QX50 or the larger, more family-friendly QX60, we have something for everyone. If you prefer a larger SUV with plenty of luxury features, the QX80 might be the perfect choice.

Want to learn more about the different configurations available for these models? You can explore all the details on the Color, Trim & Engine Options page for each vehicle. We’re happy to answer your questions, provide expert advice, and help you find the best fit for your lifestyle.

Come visit us at Infiniti of Ontario or contact us today. We look forward to helping you discover the perfect luxury SUV!